A White Paper on Nematode Comparative Genomics
Abstract
In response to the new opportunities for genome sequencing and comparative genomics, the Society of Nematology (SON) formed a committee to develop a white paper in support of the broad scientific needs associated with this phylum and interests of SON members. Although genome sequencing is expensive, the data generated are unique in biological systems in that genomes have the potential to be complete (every base of the genome can be accounted for), accurate (the data are digital and not subject to stochastic variation), and permanent (once obtained, the genome of a species does not need to be experimentally re-sampled). The availability of complete, accurate, and permanent genome sequences from diverse nematode species will underpin future studies into the biology and evolution of this phylum and the ecological associations (particularly parasitic) nematodes have with other organisms. We anticipate that upwards of 100 nematode genomes will be solved to varying levels of completion in the coming decade and suggest biological and practical considerations to guide the selection of the most informative taxa for sequencing.
Additional Information
© 2005 Society of Nematologists. Received for publication 19 July 2005. The authors are grateful for discussions with and comments from many colleagues, especially during the Genome Workshop at the 2004 Society of Nematology annual meeting, Estes Park, CO, August 2004 (Bird, 2004), and the Helminth Genome Sequencing Meeting organized by Prof. R. Maizels and held at the Sanger Institute, Cambridge, UK, March, 2004. In particular, we thank Prof. Maizels for allowing us to draw from his report of that meeting in preparing this document.Attached Files
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Additional details
- PMCID
- PMC2620993
- Eprint ID
- 95474
- Resolver ID
- CaltechAUTHORS:20190514-091645302
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2019-05-14Created from EPrint's datestamp field
- Updated
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2019-10-03Created from EPrint's last_modified field