Welcome to the new version of CaltechAUTHORS. Login is currently restricted to library staff. If you notice any issues, please email coda@library.caltech.edu
Published April 4, 2012 | Published
Journal Article Open

WormBase - Annotating many nematode genomes

Abstract

WormBase (www.wormbase.org) has been serving the scientific community for over 11 years as the central repository for genomic and genetic information for the soil nematode Caenorhabditis elegans. The resource has evolved from its beginnings as a database housing the genomic sequence and genetic and physical maps of a single species, and now represents the breadth and diversity of nematode research, currently serving genome sequence and annotation for around 20 nematodes. In this article, we focus on WormBase's role of genome sequence annotation, describing how we annotate and integrate data from a growing collection of nematode species and strains. We also review our approaches to sequence curation, and discuss the impact on annotation quality of large functional genomics projects such as modENCODE.

Additional Information

© 2012 Landes Bioscience. Submitted: 11/02/11; Revised: 02/02/12; Accepted: 02/02/12. This work is supported by the US National Institutes of Health (Grant no. P41 HG02223); US National Human Genome Research Institute (Grant no. P41-HG02223); and British Medical Research Council (Grant no. G070119); P.W.S. is an investigator with the Howard Hughes Medical Institute. Funding for open access charge: US National Human Genome Research Institute (Grant no. P41-HG02223).

Attached Files

Published - worm-1-15.pdf

Files

worm-1-15.pdf
Files (575.9 kB)
Name Size Download all
md5:f4591d53efd279333dce4640637d2bd9
575.9 kB Preview Download

Additional details

Created:
August 19, 2023
Modified:
October 20, 2023