Welcome to the new version of CaltechAUTHORS. Login is currently restricted to library staff. If you notice any issues, please email coda@library.caltech.edu
Published January 21, 2016 | public
Book Section - Chapter

The Acquisition of Cell Fate in Mouse Development: How Do Cells First Become Heterogeneous?

Abstract

Specification of cell fate in the early mouse embryo involves the generation of heterogeneities between cells in polarity, position, gene expression, and protein activity. Identifying when and how these differences first become established represents an important challenge for understanding the roles of stochastic and cell history-dependent mechanisms in mammalian development.

Additional Information

© 2016 Elsevier. Available online 21 January 2016. We thank the Wellcome Trust for supporting the work in our laboratory and Meng Zhu for comments on the manuscript.

Additional details

Created:
August 22, 2023
Modified:
January 14, 2024