Welcome to the new version of CaltechAUTHORS. Login is currently restricted to library staff. If you notice any issues, please email coda@library.caltech.edu
CaltechAUTHORS
Published December 21, 2018 | Published
Journal Article Open

Emerging evidence linking the gut microbiome to neurologic disorders

Griffiths, Jessica A. ORCID icon
Mazmanian, Sarkis K. ORCID icon

Abstract

The gut microbiome contributes to the development and function of the immune, metabolic, and nervous systems. Furthermore, commensal bacteria modulate symptoms and pathology in mouse models of neuropsychiatric and neurodevelopmental diseases. Uncovering mechanisms that are utilized by the microbiome to mediate gut–brain connections may provide novel opportunities to target therapies to the gut in order to treat neurologic disorders.

Additional Information

© The Author(s). 2018. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. First Online: 21 December 2018. The authors would like to thank Gil Sharon, Brittany Needham, Bryan Yoo, Henry Schreiber IV, Tim Sampson, and Livia Hecke Morais for critically reading and providing input on this manuscript. Research in the Mazmanian laboratory is supported by funds from Lynda and Blaine Fetter, the Heritage Medical Research Institute, the Simons Foundation (322839), and the NIH (MH100556). Authors' contributions: All of the authors contributed to writing this article and have approved the final version. The authors declare that they have no competing interests.

Attached Files

Published - Griffiths-Mazmanian2018_Article_EmergingEvidenceLinkingTheGutM.pdf

Files

Griffiths-Mazmanian2018_Article_EmergingEvidenceLinkingTheGutM.pdf
Files (520.0 kB)

Additional details

Identifiers Funding Dates Caltech Custom Metadata
Created:
August 19, 2023
Modified:
October 19, 2023