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Published December 21, 2018 | Supplemental Material
Journal Article Open

A nanozyme tag enabled chemiluminescence imaging immunoassay for multiplexed cytokine monitoring

Abstract

We report a new concept of a chemiluminescence imaging nanozyme immunoassay (CINIA), in which nanozymes are exploited as catalytic tags for simultaneous multiplex detection of cytokines. The CINIA provides a novel and universal nanozyme-labeled multiplex immunoassay strategy for high-throughput detection of relevant biomarkers and further disease diagnosis.

Additional Information

© 2018 The Royal Society of Chemistry. Received 28th September 2018 , Accepted 13th November 2018 First published on 14th November 2018. This work was financially supported by the National Natural Science Foundation of China (21475116, 21575125, 81870033, 81573220), the 333 Project and Qinglan Project of Jiangsu Province, and the High-end talent support program of Yangzhou University for Zhanjun Yang and Juan Li, the Priority Academic Program Development of Jiangsu Higher Education Institution (PAPD), the Six Talent Peaks Project of Jiangsu Province for Zhanjun Yang and Juan Li, and the Postgraduate Cultivation and Innovation Project of Jiangsu Province (KYCX17_1876) and the Foundation for Young Medical Scholar in Jiangsu Province (QNRC 2016325, 2016333). There are no conflicts to declare.

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