Published May 21, 1984
| public
Journal Article
Retzius cells retain functional membrane properties following 'ablation' by the neurotoxin 5,7-DHT
- Creators
- Lent, Charles M.
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Dickinson, Michael H.
Chicago
Abstract
The neurotoxin 5,7-dihydroxytryptamine (5,7-DHT) is generally believed to selectively ablate serotonergic neurons. Serotonin-containing Retzius cells (RZ) in the leech appear ablated by 5,7-DHT treatment. However, these brown, mis-shapen, non-fluorescent neurons retain their synaptic inputs, action potentials, electronic outputs, a membrane receptor, and axonal projections.
Additional Information
© 1984 Published by Elsevier B.V. Accepted 17 January 1984. We thank C, G. Marshall for helpful comments. Supported by PHS Grant NS-14482 to C.M.L.Additional details
- Eprint ID
- 90939
- DOI
- 10.1016/0006-8993(84)91353-2
- Resolver ID
- CaltechAUTHORS:20181116-073530126
- NIH
- NS-14482
- Created
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2018-11-16Created from EPrint's datestamp field
- Updated
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2021-11-16Created from EPrint's last_modified field