Published August 1, 2001
| public
Journal Article
Retroviruses as tools to study the immune system
Abstract
Retrovirus-based vectors provide an efficient means to introduce and express genes in cells of the immune system and have become a popular tool to study immune function. They are easy to manipulate and provide stable, long-term gene expression because they integrate into the genome. Current retroviral vectors do have limitations that affect their usefulness in certain applications. However, recent advances suggest a number of ways in which these vectors might be improved to extend their utility in immunological research.
Additional Information
© 2001 Elsevier Science Ltd. Available online 3 August 2001. The authors wish to thank David Baltimore (California Institute of Technology), Martin Scott (Biogen Inc.) and Warren Pear (University of Pennsylvania) for their helpful comments on the manuscript. LVP is supported by a Career Development Award from the Juvenile Diabetes Research Foundation and an award from the David Koch Research Fund; CL is funded by the Christopher Reeves Paralysis Foundation, YR is a Merck Fellow of the Life Sciences Foundation and X-FQ is funded by a Damon Runyon-Walter Winchell Fellowship (DRG 1568).Additional details
- Eprint ID
- 89969
- Resolver ID
- CaltechAUTHORS:20180926-140405562
- Juvenile Diabetes Research Foundation
- David Koch Research Fund
- Christopher Reeves Paralysis Foundation
- Life Sciences Foundation
- DRG 1568
- Damon Runyon-Walter Winchell Cancer Fund
- Created
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2018-09-26Created from EPrint's datestamp field
- Updated
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2021-11-16Created from EPrint's last_modified field