Genetics in non-genetic model systems
- Creators
- Lois, Carlos
- Groves, James O.
Abstract
The past few decades have seen the field of genetic engineering evolve at a rapid pace, with neuroscientists now equipped with a wide range of tools for the manipulation of an animal's genome in order to study brain function. However, the number of species to which these technologies have been applied, namely the fruit fly, C. elegans, zebrafish and mouse, remains relatively few. This review will discuss the variety of approaches to genetic modification that have been developed in such traditional 'genetic systems', and highlight the progress that has been made to translate these technologies to alternative species such as rats, monkeys and birds, where certain neurobiological questions may be better studied.
Additional Information
© 2011 Elsevier Ltd. Available online 24 November 2011.Attached Files
Accepted Version - nihms337166.pdf
Files
Name | Size | Download all |
---|---|---|
md5:2435b1a6d17a31cccf06c055d13d4161
|
52.1 kB | Preview Download |
Additional details
- PMCID
- PMC3320209
- Eprint ID
- 89968
- Resolver ID
- CaltechAUTHORS:20180926-140008893
- Created
-
2018-09-26Created from EPrint's datestamp field
- Updated
-
2021-11-16Created from EPrint's last_modified field