A fast 512-element ring array photoacoustic imaging system for small animals
Abstract
A 512-element photoacoustic tomography system for small animal imaging using a ring ultrasound array has been developed. The system features a 5 MHz piezocomposite transducer array formed into a complete circular aperture. Custom receiver electronics consisting of dedicated preamplifiers, 8:1 multiplexed post-amplifiers, and a 64-channel data acquisition module provide full tomographic imaging at up to 8 frames/second. We present details of the system design along with characterization results of the resolution, imaging volume, and sensitivity. Small animal imaging performance is demonstrated through images of mice brain vasculature at different depths and real-time spectroscopic scans. This system enables real-time tomographic imaging for functional photoacoustic studies for the first time.
Additional Information
© 2009 Society of Photo-Optical Instrumentation Engineers (SPIE). We acknowledge partial support from NIH grants NIH R01EB002136 and the Patrick and Catherine Weldon Donaghue Research Foundation.Attached Files
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Additional details
- Eprint ID
- 89871
- Resolver ID
- CaltechAUTHORS:20180921-100906012
- NIH
- R01 EB002136
- Patrick and Catherine Weldon Donaghue Research Foundation
- Created
-
2018-09-24Created from EPrint's datestamp field
- Updated
-
2021-11-16Created from EPrint's last_modified field
- Series Name
- Proceedings of SPIE
- Series Volume or Issue Number
- 7177