Photoacoustic Doppler axial flow measurement of homogenous media using structured illumination

Creators: Zhang, Ruiying; Yao, Junjie; Maslov, Konstantin I.; Wang, Lihong V.

Others:: Oraevsky, Alexander A.; Wang, Lihong V.

Abstract

We propose time and frequency domain methods for homogenous flow measurement based on the photoacoustic Doppler effect. Excited by spatially modulated laser pulses, the flowing medium induces a Doppler frequency shift in the received photoacoustic signals. The frequency shift is proportional to the component of the flow speed projected onto the acoustic beam axis. These methods do not rely on particle heterogeneity in the medium. A red-ink phantom flowing in a tube immersed in water was used to validate the methods in both frequency and time domains.

Additional Information

© 2014 Society of Photo-Optical Instrumentation Engineers (SPIE). This research was supported by the National Institutes of Health Grants DP1 EB016986 (NIH Director's Pioneer Award), R01 EB008085, R01 CA134539, U54 CA136398, R01 CA157277, R01 CA159959. L.V.W. has a financial interest in Microphotoacoustics, Inc. and Endra, Inc., which, however, did not support this work. K.M. has a financial interest in Microphotoacoustics, Inc., which, however, did not support this work. The authors would like to thank Ms. Seema Dahlheimer for her close reading of the manuscript. We also appreciate technical assistance from and useful discussions with Lidai Wang, Yong Zhou, Jinyang Liang, Wenxin Xing, Arie Krumholz, and Yan Liu.

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