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Published June 2016 | Published
Journal Article Open

Tutorial on photoacoustic tomography

Abstract

Photoacoustic tomography (PAT) has become one of the fastest growing fields in biomedical optics. Unlike pure optical imaging, such as confocal microscopy and two-photon microscopy, PAT employs acoustic detection to image optical absorption contrast with high-resolution deep into scattering tissue. So far, PAT has been widely used for multiscale anatomical, functional, and molecular imaging of biological tissues. We focus on PAT's basic principles, major implementations, imaging contrasts, and recent applications.

Additional Information

© 2016 Society of Photo-Optical Instrumentation Engineers. Paper 160054SSTR received Jan. 26, 2016; accepted for publication Mar. 22, 2016; published online Apr. 18, 2016. The authors would like to thank Professor James Ballard for manuscript editing. This work was sponsored in part by National Institutes of Health Grant Nos. DP1 EB016986 (NIH Director's Pioneer Award), R01 CA186567 (NIH Director's Transformative Research Award), and S10 RR026922. L. V. W. has a financial interest in Microphotoacoustics, Inc., which, however, did not support this work.

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August 22, 2023
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