Welcome to the new version of CaltechAUTHORS. Login is currently restricted to library staff. If you notice any issues, please email coda@library.caltech.edu
Published April 1, 1999 | public
Journal Article

Directed evolution of industrial enzymes

Abstract

Directed evolution has emerged in just a few years as one of the most effective approaches to adapting biocatalysts to the performance requirements of industrial and medical applications. Directed evolution mimics the processes of Darwinian evolution in a test tube, combining random mutagenesis and/or recombination with screening or selection for enzyme variants that have the desired properties1. A recent conference* that convened practitioners from industry and academia surveyed current efforts and highlighted the rapid progress the field has enjoyed. In addition to impressive demonstrations of enzyme engineering, there were a variety of challenging problems and approaches to laboratory evolution.

Additional Information

© 1999 Published by Elsevier.

Additional details

Created:
August 22, 2023
Modified:
October 18, 2023