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Published February 1, 1999 | public
Journal Article

Directed evolution of biocatalysts

Abstract

Directed evolution is being used increasingly in academic and industrial laboratories to modify and improve important biocatalysts. Significant advances during this period of review include compartmentalization of genes and the in vitro translation apparatus in emulsions, as well as several impressive demonstrations of catalyst improvement. Shuffling of homologous genes offers a new way to utilize natural diversity in the evolution of novel catalysts.

Additional Information

© 1999 Elsevier Science Ltd. The authors wish to acknowledge support for directed evolution research provided by the Office of Naval Research and the Army Research Office, USA.

Additional details

Created:
August 19, 2023
Modified:
October 18, 2023