Published March 26, 1998
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Microfabricated devices for sizing DNA and sorting cells
- Other:
- Gourley, Paul Lee
Chicago
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Abstract
We have microfabricated devices to size and sort microscopic biological objects, ranging from cells to single molecules of DNA. Sizing is accomplished by fluorescent excitation and detection. The devices are fabricated in a silicone elastomer using a replica method. Single molecules of DNA have been sized to 10 percent accuracy, and manipulation of E. Coli cells has been demonstrated.
Additional Information
© 1998 Society of Photo-Optical Instrumentation Engineers (SPIE). We thank Anne Fu and Frances Arnold for the gift of fluorescent E Coli cells.Attached Files
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Additional details
- Eprint ID
- 87694
- Resolver ID
- CaltechAUTHORS:20180710-102548857
- Created
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2018-07-10Created from EPrint's datestamp field
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2021-11-15Created from EPrint's last_modified field
- Series Name
- Proceedings of SPIE
- Series Volume or Issue Number
- 3258