Published January 18, 1983
| public
Book Section - Chapter
Single-Cell Metabolic Model Determination by Analysis of Microbial Populations
- Creators
- Bailey, James E.
Chicago
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Abstract
The properties of microbial populations result from the characteristics of metabolism and its control at the level of the individual cell. Useful descriptions of population behavior may therefore be constructed based on understanding of single-cell metabolism, and, conversely, studies of population properties may be employed to extract information about single-cell operation. Population balance equations provide the primary mathematical tool for these purposes, and flow cytometry allows experimental access to the distribution of cell states in the population. Application of these methods to bacteria and yeasts is illustrated using three example systems.
Additional Information
© 1983 American Chemical Society. Received July 22, 1982. Published in print 18 January 1983. The author is extremely indebted to his colleagues and students, D. McQuitty, Y. Nishimura, D. Agar, M. Hjortso, J. Fazel-Madjlessi, M. Gilbert, A. Bartel, L. Y. Lee, and J. Oro, for their central role in the research described in this paper and to the National Science Foundation for financial support of this research.Additional details
- Eprint ID
- 85614
- Resolver ID
- CaltechAUTHORS:20180404-143706256
- NSF
- Created
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2018-04-04Created from EPrint's datestamp field
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2021-11-15Created from EPrint's last_modified field
- Series Name
- ACS Symposium Series
- Series Volume or Issue Number
- 207