Synthetic micro/nanomotors in drug delivery
- Creators
-
Gao, Wei
- Wang, Joseph
Abstract
Nanomachines offer considerable promise for the treatment of diseases. The ability of man-made nanomotors to rapidly deliver therapeutic payloads to their target destination represents a novel nanomedicine approach. Synthetic nanomotors, based on a multitude of propulsion mechanisms, have been developed over the past decade toward diverse biomedical applications. In this review article, we journey from the use of chemically powered drug-delivery nanovehicles to externally actuated (fuel-free) drug-delivery nanomachine platforms, and conclude with future prospects and challenges for such practical propelling drug-delivery systems. As future micro/nanomachines become more powerful and functional, these tiny devices are expected to perform more demanding biomedical tasks and benefit different drug delivery applications.
Additional Information
© 2014 The Royal Society of Chemistry. Received 6th June 2014 , Accepted 30th June 2014. First published on 3rd July 2014. This project received support from the Defense Threat Reduction Agency-Joint Science and Technology Office for Chemical and Biological Defense (Grant no. HDTRA1-13-1-0002). W.G. is a HHMI International Student Research fellow.Attached Files
Published - c4nr03124e.pdf
Files
| Name | Size | Download all |
|---|---|---|
|
md5:a866b857f681b9266e1c4eb3bb6c1201
|
2.1 MB | Preview Download |
Additional details
- Eprint ID
- 84462
- Resolver ID
- CaltechAUTHORS:20180122-140705351
- Defense Threat Reduction Agency (DTRA)
- HDTRA1-13-1-0002
- Howard Hughes Medical Institute (HHMI)
- Created
-
2018-01-23Created from EPrint's datestamp field
- Updated
-
2021-11-15Created from EPrint's last_modified field