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Published April 4, 2014 | Published
Patent Open

Imidazo bibyclic imminium compounds as antitumor agents

Abstract

The invention relates to imidazobicycles having a quaternary nitrogen that are inhibitors of the Hedgehog pathway and therefore useful as antitumor agents and as probes of the function of Hedgehog-dependent systems.

Additional Information

Appl. No.: 14/409,683 Filed: June 19, 2013 PCT Filed: June 19, 2013 PCT No.: PCT/US2013/046560 371(c)(1),(2),(4) Date: December 19, 2014 PCT Pub. No.: WO2013/192301 PCT Pub. Date: December 27, 2013. Government Interests: This invention was made with Government support under contract CA136574 awarded by the National Institutes of Health. The Government has certain rights in this invention. Parent Case Text: This application is a national phase filing under 35 U.S.C. .sctn.371 of PCT International Application PCT/US2013/046560, filed Jun. 19, 2013, and published under PCT Article 21(2) as WO 2013/192301 on Dec. 27, 2013. PCT/US2013/046560 claims priority from U.S. provisional application 61/662,977, filed Jun. 22, 2012. The contents of each of the prior applications are incorporated herein by reference in their entirety.

Attached Files

Published - EP2864332B1.pdf

Published - US9611276B2.pdf

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US9611276B2.pdf
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Additional details

Created:
August 20, 2023
Modified:
October 20, 2023