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Published August 2017 | Accepted Version
Journal Article Open

Rules of the road for insect gene drive research and testing

Abstract

Approximately two years ago, two of us (E.B. and V.G.) demonstrated the first experimental application of CRISPR–Cas9 to 'drive' a desired trait throughout a population of fruit flies. In November 2015, this same team at the University of California, San Diego, joined with A.A.J. and others at the University of California, Irvine, to develop a CRISPR-based gene drive for population modification of the malaria vector mosquito Anopheles stephensi. A month later, a group in the United Kingdom applied a CRISPR-based gene drive to another malaria vector, Anopheles gambiae.

Additional Information

© 2017 Nature America, Inc. Published online 08 August 2017. This Correspondence represents the views of the authors only, and not necessarily those of the entities with which they are affiliated. The authors declare competing financial interests: details are available in the online version of the paper.

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Created:
August 19, 2023
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October 17, 2023