Published May 15, 2008
| Accepted Version + Supplemental Material
Journal Article
Open
A Facile Preparation of Imidazolinium Chlorides
- Creators
- Kuhn, Kevin M.
- Grubbs, Robert H.
Abstract
A process for the preparation of symmetric and unsymmetric imidazolinium chlorides that involves reaction of a formamidine with dichloroethane and a base (a) is described. This method makes it possible to obtain numerous imidazolinium chlorides under solvent-free reaction conditions and in excellent yields with purification by simple filtration. Alternatively, symmetric imidazolinium chlorides can be prepared directly in moderate yields from substituted anilines by utilizing half of the formamidine intermediate as sacrificial base (b).
Additional Information
© 2008 American Chemical Society. Received 18 March 2008. Published online 16 April 2008. Published in print 1 May 2008. We gratefully acknowledge financial support from NIH Grant No. GM31332 to R.H.G.Attached Files
Accepted Version - nihms97659.pdf
Supplemental Material - ol800628a-file003.pdf
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nihms97659.pdf
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Additional details
- PMCID
- PMC2666923
- Eprint ID
- 76947
- Resolver ID
- CaltechAUTHORS:20170426-104049362
- GM31332
- NIH
- Created
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2017-04-26Created from EPrint's datestamp field
- Updated
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2021-11-15Created from EPrint's last_modified field