Welcome to the new version of CaltechAUTHORS. Login is currently restricted to library staff. If you notice any issues, please email coda@library.caltech.edu
Published November 21, 2007 | Accepted Version
Journal Article Open

Retinal Adaptation to Object Motion

Abstract

Due to fixational eye movements, the image on the retina is always in motion, even when one views a stationary scene. When an object moves within the scene, the corresponding patch of retina experiences a different motion trajectory than the surrounding region. Certain retinal ganglion cells respond selectively to this condition, when the motion in the cell's receptive field center is different from that in the surround. Here we show that this response is strongest at the very onset of differential motion, followed by gradual adaptation with a time course of several seconds. Different subregions of a ganglion cell's receptive field can adapt independently. The circuitry responsible for differential motion adaptation lies in the inner retina. Several candidate mechanisms were tested, and the adaptation most likely results from synaptic depression at the synapse from bipolar to ganglion cell. Similar circuit mechanisms may act more generally to emphasize novel features of a visual stimulus.

Additional Information

© 2007 Elsevier Inc. Received 12 January 2007, Revised 14 May 2007, Accepted 26 September 2007, Available online 21 November 2007; Published: November 20, 2007. We thank Dr Mihai Manu for help with bipolar cell recordings. This work was supported by the Harvard Society of Fellows (B.P.Ö.), an NRSA postdoctoral fellowship (S.A.B.), and grants from the NIH (M.M.).

Attached Files

Accepted Version - nihms34816.pdf

Files

nihms34816.pdf
Files (2.4 MB)
Name Size Download all
md5:fc205876b864878cbb642378f1565b0e
2.4 MB Preview Download

Additional details

Created:
August 22, 2023
Modified:
October 25, 2023