Plasma components which mediate cellular defences in the gastropod mollusc Biomphalaria glabrata
Abstract
Blood plasmas from certain strains of Biomphalariaglabrata are known to have components which facilitate a hemocyte-effected cytotoxic response against encapsulated Schistosomamansoni sporocysts. The possible identity of the factor(s) has been investigated. Sporocysts placed in snail plasma rapidly acquire a wide variety of host plasma antigens, at least some of which are displayed on the parasite surface. Plasmas from strains of snail resistant to the parasite agglutinate fixed sporocysts, while plasmas from susceptible strains fail to do so. Fixed sporocysts incubated in plasma bind selectively a subpopulation of plasma antigens; some are bound uniquely in resistant plasma. Another resembles a hemagglutinin from snail plasma. These and other recently acquired data are discussed in light of increasing evidence for defensive roles of multivalent lectins.
Additional Information
© 1985 Elsevier Ltd. This paper summarises a talk presented to the American Society of Zoologists, Division of Developmental and Comparative Immunology in Denver, CO. Dec. 1984, and is based on work published in other (cited) primary papers.Additional details
- Eprint ID
- 74753
- Resolver ID
- CaltechAUTHORS:20170303-165215438
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2017-03-17Created from EPrint's datestamp field
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2021-11-11Created from EPrint's last_modified field