Published March 20, 2008
| Supplemental Material + Accepted Version
Journal Article
Open
Homogeneous Pd-Catalyzed Enantioselective Decarboxylative Protonation
Abstract
General homogeneous conditions for the palladium-catalyzed synthesis of carbonyl compounds with tertiary carbon stereocenters at the α-position are reported. The highly reactive catalyst tolerates a variety of substrate substitution and functionality, and generates enantioenriched cyclic ketones from racemic allyl β-ketoester starting materials.
Additional Information
© 2008 American Chemical Society. Received November 21, 2007. Publication Date (Web): February 28, 2008. We thank Sankyo Co., Ltd. (financial support of T.N.), Eli Lilly (predoctoral fellowship to J.T.M.), Amgen, and Bristol-Myers Squibb for generous funding.Attached Files
Accepted Version - nihms243551.pdf
Supplemental Material - ol702821j-file003.pdf
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ol702821j-file003.pdf
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Additional details
- PMCID
- PMC2966305
- Eprint ID
- 74444
- Resolver ID
- CaltechAUTHORS:20170221-162726154
- Sankyo Co., Ltd.
- Eli Lilly
- Amgen
- Bristol-Myers Squibb
- Created
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2017-02-22Created from EPrint's datestamp field
- Updated
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2021-11-11Created from EPrint's last_modified field