Pulsed-microwave-induced thermoacoustic tomography: Filtered backprojection in a circular measurement configuration
- Creators
- Xu, Minghua
-
Wang, Lihong V.
Abstract
Our study on pulsed-microwave-induced thermoacoustic tomography in biological tissues is presented. A filtered backprojection algorithm based on rigorous theory is used to reconstruct the cross-sectional image from a thermoacoustic measurement in a circular configuration that encloses the sample under study. Specific details describing the measurement of thermoacoustic waves and the implementation of the reconstruction algorithm are discussed. A two-dimensional (2D) phantom sample with 2 mm features can be imaged faithfully. Through numerical simulation, the full width half-maximum (FWHM) of the point-spread function (PSF) is calculated to estimate the spatial resolution. The results demonstrate that the circular measurement configuration combined with the filtered backprojection method is a promising technique for detecting small tumors buried in biological tissues by utilizing microwave absorption contrast and ultrasound spatial resolution (∼mm).
Additional Information
© 2002 American Association of Physicists in Medicine. Received 12 December 2001; accepted for publication 7 May 2002; published 16 July 2002. This project was sponsored in part by the U.S. Army Medical Research and Material Command Grant No. DAMD17-00-1-0455, the National Institutes of Health Grant No. R01 CA71980, the National Science Foundation Grant No. BES-9734491, and Texas Higher Education Coordinating Board Grant No. ARP 000512-0123-1999.Additional details
- Eprint ID
- 73945
- DOI
- 10.1118/1.1493778
- Resolver ID
- CaltechAUTHORS:20170201-140855040
- Army Medical Research and Materiel Command
- DAMD17-00-1-0455
- NIH
- R01 CA71980
- NSF
- BES-9734491
- Texas Higher Education Coordinating Board
- ARP 000512-0123-1999
- Created
-
2017-02-02Created from EPrint's datestamp field
- Updated
-
2021-11-11Created from EPrint's last_modified field