Published November 7, 2016
| public
Journal Article
Signaling Boundary Conditions Drive Self-Organization of Human "Gastruloids"
- Creators
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Thomson, Matthew
Chicago
An error occurred while generating the citation.
Abstract
Morphogenesis requires tissues to sense and respond to their geometry. In this issue of Developmental Cell, Etoc et al. (2016) show that a confined colony of human embryonic stem cells can spontaneously sense its boundary, generating a self-organized TGF-β signaling gradient that patterns it into a tissue resembling a gastrulating embryo.
Additional Information
© 2016 Elsevier Inc. Available online 7 November 2016.Additional details
- Eprint ID
- 72187
- DOI
- 10.1016/j.devcel.2016.10.016
- Resolver ID
- CaltechAUTHORS:20161121-084221387
- Created
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2016-11-21Created from EPrint's datestamp field
- Updated
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2021-11-11Created from EPrint's last_modified field