Published August 15, 2006
| Published
Journal Article
Open
In vivo three-dimensional photoacoustic tomography of a whole mouse head
Chicago
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Abstract
An in vivo photoacoustic imaging system was designed and implemented to image the entire small animal head. A special scanning gantry was designed to enable in vivo imaging in coronal cross sections with high contrast and good spatial resolution for the first time to our knowledge. By use of a 2.25 MHz ultrasonic transducer with a 6 mm diameter active element, an in-plane radial resolution of ∼312 µm was achieved. Deeply seated arterial and venous vessels in the head measuring up to 1.7 cm in diameter were simultaneously imaged in vivo with 804 nm wavelength laser excitation of photoacoustic waves.
Additional Information
© 2006 Optical Society of America. Received April 4, 2006; revised May 15, 2006; accepted May 17, 2006; posted May 26, 2006 (Doc. ID 69679); published July 25, 2006. We thank Jung-Taek Oh, Meng-Lin Li, Konstantin Maslov, Geng Ku, and Xueyi Xie for technical assistance and Sergiu V. Similache for assistance with animal handling. The project was sponsored by National Institutes of Health grants R01 EB000712 and R01 NS46214.Attached Files
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Additional details
- Eprint ID
- 71899
- Resolver ID
- CaltechAUTHORS:20161109-154531350
- NIH
- R01 EB000712
- NIH
- R01 NS46214
- Created
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2016-11-09Created from EPrint's datestamp field
- Updated
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2021-11-11Created from EPrint's last_modified field