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Published June 1991 | public
Book Section - Chapter

A systolic array processor for biological information signal processing

Abstract

The Biological Information Signal Processing (BISP) is a system for high speed sequence comparisons designed to support the computation requirements for mapping and sequencing the human and other genomes. The heart of a BISP system is a versatile processor chip that can conduct the most time consuming sequence comparison functions, establishing both global and local relationships between two DNA or protein sequences. Because of the application's strong computation and communication requirements, a programmable systolic array architecture was developed. A BISP system can include a large number of processing elements; the initial BISP demonstration system consists of 768 BISP elements, capable of delivering more than 6.25 x 10^9 integer operations per second. The system can be expanded to include over 4,000 elements, This paper describes the comparison algorithm and outlines the BISP chip and system designs. Estimated performance of the BISP system is compared with several different computer architectures.

Additional Information

© 1991 ACM. The research described in this paper was carried out by the Jet Propulsion Laboratory, California Institute of Technology, and University of Southern California, and was sponsored by National Science Foundation, Department of Energy, and National Institutes of Health.

Additional details

Created:
August 20, 2023
Modified:
October 20, 2023