Published August 25, 2016
| public
Journal Article
Tag Team Ubiquitin Ligases
- Creators
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Kleiger, Gary
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Deshaies, Raymond
Chicago
An error occurred while generating the citation.
Abstract
Cullin-RING (CRL) and RING1-IBR-RING2 (RBR) are two distinct types of ubiquitin ligases. In this issue, Scott et al. show that CRLs activate the RBR enzyme ARIH1 to initiate ubiquitin chains on CRL substrates, thereby marking an unexpected and important advance in our understanding of both enzymes.
Additional Information
© 2016 Elsevier Inc. R.J.D. is a founder, shareholder, and member of the scientific advisory board of Cleave Biosciences.Additional details
- Eprint ID
- 69980
- DOI
- 10.1016/j.cell.2016.08.014
- Resolver ID
- CaltechAUTHORS:20160829-080930690
- Howard Hughes Medical Institute (HHMI)
- Created
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2016-08-29Created from EPrint's datestamp field
- Updated
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2021-11-11Created from EPrint's last_modified field