Published June 2015
| public
Book Section - Chapter
MEMS for single-islet electroisletogram
Abstract
This paper reports the first MEMS device designed for in vitro measuring of electroisletogram (EIG) of individual rat islets. Using vacuum to hold an islet in proximity to a microelectrode, strong EIG signals in millivolt range are obtained, while the noise is about 100μV pk-pk. This work proves the feasibility of using MEMS and EIG for high-throughput screening, in contrast to patch-clamp measurements, of islets for transplantation to treat diabetes.
Additional Information
© 2015 IEEE. The authors would greatly thank all the members of California Institute of Technology (Caltech) MEMS lab, especially Mr. Trevor Roper for the maintenance of equipment.Additional details
- Eprint ID
- 69954
- DOI
- 10.1109/TRANSDUCERS.2015.7180865
- Resolver ID
- CaltechAUTHORS:20160826-090759324
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2016-08-26Created from EPrint's datestamp field
- Updated
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2021-03-24Created from EPrint's last_modified field