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Published March 15, 2014 | Published
Journal Article Open

Urogenital photoacoustic endoscope

Abstract

Photoacoustic (PA) endoscopy for human urogenital imaging has the potential to diagnose many important diseases, such as endometrial and prostate cancers. We have specifically developed a 12.7 mm diameter, rigid, side-scanning PA endoscopic probe for such applications. The key features of this endoscope are the streamlined structure for smooth cavity introduction and the proximal actuation mechanism for fast scanning. Here we describe the probe's composition and scanning mechanism and present in vivo experimental results suggesting its potential for comprehensive clinical applications.

Additional Information

© 2014 Optical Society of America. Received December 30, 2013; accepted January 26, 2014; posted February 10, 2014 (Doc. ID 203801); published March 10, 2014. We thank Prof. James Ballard for his attentive reading of the manuscript. This work was sponsored in part by National Institutes of Health grants DP1 EB016986 (NIH Director's Pioneer Award), R01 CA134539, and R01 CA159959. L. W. has a financial interest in Microphotoacoustics, Inc. and Endra, Inc., which, however, did not support this work. K. M. has a financial interest in Microphotoacoustics, Inc.

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