Published October 1964
| public
Journal Article
The Replication of Bacteriophage MS2 II. An in vivo Specificity for the Synthesis of Infective RNA
Chicago
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Abstract
Multiple infection with wild-type MS2 and a plaque-morphology mutant of MS2 is demonstrated. An infectivity assay for phage RNA is described and growth curves for intracellular infective RNA in MS2-infected cells are presented which demonstrate the presence of a pool of infective RNA prior to the appearance of progeny virus particles. Experiments are described which indicate that the synthetic system established in an MS2-infected cell will not be used to produce infective RNA of a genetically distinguishable superinfecting phage.
Additional Information
© 1964 Elsevier Ltd. Received 19 March 1964. This research was supported, in part, by a grant (RG-6965) from the U.S. Public Health Service. One of us (J. E. D.) was a postdoctoral fellow of the U.S. Public Health Service during part of this research period.Additional details
- Eprint ID
- 67827
- DOI
- 10.1016/S0022-2836(64)80022-X
- Resolver ID
- CaltechAUTHORS:20160610-103646469
- U.S. Public Health Service (USPHS)
- RG-6965
- U.S. Public Health Service (USPHS) Postdoctoral Fellow
- Created
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2016-06-10Created from EPrint's datestamp field
- Updated
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2021-11-11Created from EPrint's last_modified field