The Biochemistry of Genetic Factors

Abstract

The term genetic chemistry will be used in this chapter to refer to knowledge of the structure, function, replication, mode of expression, and modification of the genetic elements. The genetic elements are presently conceived to include double-stranded DNA as the genetic substance of the great majority of living organisms, single-stranded DNA as the genetic substance of certain bacterial viruses, and single-stranded RNA as the genetic substance of certain plant and animal viruses. Of necessity, discussion of the structure. replication, and expression (through the transfer of information) of these substances involves consideration of related ancillary structures, such as chromosomes and viral components. In addition to direct approaches, studies of the products of genetic action can be used as a basis for inference concerning the organization of the genetic substance, particularly when obtained under defined genetic circumstances.

Additional details