Published October 28, 1987
| public
Journal Article
Metalloregulation in the sequence specific binding of synthetic molecules to DNA
- Creators
- Griffin, John H.
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Dervan, Peter B.
Chicago
An error occurred while generating the citation.
Abstract
Specific metal cations exert remarkable effects on the transcription of several prokaryotic and eukaryotic genes. Recently, the DNA-binding eukaryotic transcription factor TFIIIA has been characterized as a series of peptide fingers connected by zinc-binding domains. These observations raise the issue of whether the binding of synthetic molecules to DNA could in some way be regulated by the addition of specific metal ions.
Additional Information
© 1987 American Chemical Society. Received April 10, 1987. We are grateful to the National Institutes of Health for research support (GM 27681} and to the National Science Foundation for a predoctoral fellowship to J.H.G.Additional details
- Eprint ID
- 67010
- Resolver ID
- CaltechAUTHORS:20160511-144439605
- NIH
- GM-27681
- NSF Predoctoral Fellowship
- Created
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2016-05-19Created from EPrint's datestamp field
- Updated
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2021-11-11Created from EPrint's last_modified field