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Published November 25, 1987 | public
Journal Article

A synthetic peptide binds 16 base pairs of A,T double helical DNA

Abstract

One approach to the design of synthetic sequence specific DNA binding molecules that bind large sequences of double helical DNA is to couple together DNA binding domains of similar or diverse base pairs specificities. The DNA binding domains should be linked together in a way that allows simultaneous binding of the units to contiguous DNA sequences.

Additional Information

© 1987 American Chemical Society. Received August 3, 1987. We are grateful to the National Institutes of Health for research support (GM-27681).

Additional details

Created:
August 19, 2023
Modified:
October 18, 2023