Published December 1, 1999
| public
Journal Article
Sequence-specific DNA recognition by polyamides
- Creators
-
Dervan, Peter B.
- Bürli, Roland W.
Chicago
An error occurred while generating the citation.
Abstract
Sequence-specific DNA-binding small molecules that can permeate cells could potentially regulate transcription of specific genes. Simple pairing rules for the minor groove of the double helix have been developed that allow the design of ligands for predetermined DNA sequences. Some of these polyamides have been shown to inhibit specific gene expression in mammalian cell culture.
Additional Information
© 1999 Elsevier Science Ltd. The work described in this review from our group was supported by the National Institutes of Health.Additional details
- Eprint ID
- 66851
- DOI
- 10.1016/S1367-5931(99)00027-7
- Resolver ID
- CaltechAUTHORS:20160510-091115065
- NIH
- Created
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2016-05-17Created from EPrint's datestamp field
- Updated
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2021-11-11Created from EPrint's last_modified field