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Published June 2003 | public
Journal Article

Recognition of the DNA minor groove by pyrrole-imidazole polyamides

Abstract

Many diseases, such as cancer, are related to aberrant gene expression. Regulating transcription by chemical methods could be important in human medicine. Minor groove-binding polyamides offer one chemical approach to DNA recognition.

Additional Information

© 2003 Elsevier. Available online 11 June 2003. The work described in this review was supported by the National Institutes of Health. BSE is supported by a predoctoral fellowship from the Howard Hughes Medical Institute.

Additional details

Created:
August 19, 2023
Modified:
October 18, 2023