Published December 2001
| public
Journal Article
Id4 expression and its relationship to other Id genes during avian embryonic development
Chicago
Abstract
We present the sequence and expression pattern of chick Id4 and compare its distribution to that of other vertebrate Id genes. At early stages, Id4 expression is discrete, with transcript transiently expressed in subsets of migrating neural crest cells, the dorsal myocardium, the segmental plate mesoderm, and the tail bud. Later, expression is also observed in the telencephalic vesicles and corneal epithelium. Of all the Id genes, Id4 exhibits the most restricted pattern in the developing nervous system, with little expression in the presumptive neural crest or placodes. Id4 appears in the neural tube much later than other Id genes. However, all four Id genes display overlapping patterns in the branchial arches and tail bud.
Additional Information
© 2001 Elsevier Science Ltd. Received 15 June 2001; received in revised form 11 September 2001; accepted 13 September 2001. Available online 9 October 2001. We thank Drs Clare Baker and John Sechrist for critical comments on the manuscript, Dr Laura Gammill for sharing unpublished arrayed library, and other M.B.-F. colleagues for generous help. This work was supported by RO1 HD DE-13223 to M.B.-F. Y.K. is supported by a fellowship from American Heart Association.Additional details
- Eprint ID
- 64945
- DOI
- 10.1016/S0925-4773(01)00576-7
- Resolver ID
- CaltechAUTHORS:20160302-071130549
- NIH
- RO1 HD DE-13223
- American Heart Association
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2016-03-02Created from EPrint's datestamp field
- Updated
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2021-11-10Created from EPrint's last_modified field