Conservation of Pax gene expression in ectodermal placodes of the lamprey
Abstract
Ectodermal placodes contribute to the cranial ganglia and sense organs of the head and, together with neural crest cells, represent defining features of the vertebrate embryo. The identity of different placodes appears to be specified in part by the expression of different Pax genes, with Pax-3/7 class genes being expressed in the trigeminal placode of mice, chick, frogs and fish, and Pax-2/5/8 class genes expressed in the otic placode. Here, we present the cloning and expression pattern of lamprey Pax-7 and Pax-2, which mark the trigeminal and otic placodes, respectively, as well as other structures characteristic of vertebrate Pax genes. These results suggest conservation of Pax genes and placodal structures in basal and derived vertebrates.
Additional Information
© 2002 Elsevier Science B.V. Received 27 August 2001; received in revised form 4 December 2001; accepted 12 December 2001. Available online 15 March 2002. Received by R. Di Lauro. We thank Roger Bergstedt and the staff of Hammond Bay Biological Station and Dr. Jim Langeland for assistance in collection of embryos, Burcu Babaoglan for assistance with LampPax-2 in situs and library screening, and Dan Meulemans for excellent technical assistance. This work was supported by NASA grant 98-HEDS-02 to MBF.Additional details
- Eprint ID
- 64942
- Resolver ID
- CaltechAUTHORS:20160302-071129792
- 98-HEDS-02
- NASA
- Created
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2016-03-02Created from EPrint's datestamp field
- Updated
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2021-11-10Created from EPrint's last_modified field