Published June 2002 | public
Journal Article

Convergent Extension: The Molecular Control of Polarized Cell Movement during Embryonic Development

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Abstract

During development, vertebrate embryos undergo dramatic changes in shape. The lengthening and narrowing of a field of cells, termed convergent extension, contributes to a variety of morphogenetic processes. Focusing on frogs and fish, we review the different cellular mechanisms and the well-conserved signaling pathways that underlie this process.

Additional Information

© 2002 Cell Press. Available online 19 June 2002. The authors thank Ray Keller, L. Solnica-Krezel, M.E. Lane, Y. Gong, M. Grow, and the anonymous reviewers for critical reading of the manuscript and helpful discussions, and Robert Zinzen for translation of German texts. J.B.W. is supported by the American Cancer Society (PF-99-350-01-DDC).

Additional details

Created:
August 19, 2023
Modified:
October 17, 2023