Published May 1995 | public
Journal Article

Lipopolysaccharide activates the sea urchin immune system

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Abstract

Profilin is a small, actin-binding protein that functions at the intersection of signal transduction and cytoskeletal modifications. Increases in the number of profilin messages per cell correlate with sea urchin coelomocyte activation in response to injury. Here we show that coelomocytes respond to immune challenge from lipopolysaccharide with significant elevations in profilin transcripts per coelomocyte.

Additional Information

© 1995 Elsevier. (Submitted February 1995; accepted April 1995) The authors wish to acknowledge the useful comments of the anonymous reviewers. This work was supported by a grant from NSF (No. MCB 9219330).

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August 22, 2023
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October 25, 2023