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Published April 1969 | Published
Journal Article Open

Isolation of a Chloramphenicol-Resistant Protein From λ-Infected Cells

Abstract

During infection with bacteriophage ϕX174, a protein, made in the presence of 30 γ chloramphenicol/ml but not made in the presence of concentrations greater than 100 γ/ml, has been shown to be essential for viral DNA replication. A protein with similar chromatographic properties and "chloramphenicol resistance" has now been demonstrated in cells infected with λ bacteriophage.

Additional Information

© 1969 National Academy of Sciences. Communicated December 23, 1968. One of us (A. J. L.) was a postdoctoral fellow of the U.S. Public Health Service. This research was supported in part by grant GM 13554 from the U.S. Public Health Service.

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August 19, 2023
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