Published July 28, 1978
| public
Journal Article
Differential Rates of Proton Exchange for the Guanidinium Nitrogens of L-Arginine Determined by Natural-Abundance Nitrogen-15 Nuclear Magnetic Resonance Spectroscopy
- Creators
- Yavari, Issa
- Roberts, John D.
Chicago
An error occurred while generating the citation.
Abstract
Differential rates of N-H proton-exchange reactions have been determined for the guanidinium nitrogens of l-arginine, 1̂, in the pH range of 0.5 to 11.5 by natural-abundance nitrogen-15 NMR spectroscopy. Base-catalyzed N-H proton exchange of the -NH- group is found to be two times faster than for the guanidino -NH_2 groups. The results can be rationalized by consideration of the contributions of various valence-bond structures to the resonance hybrid of 1.
Additional Information
© 1978 Academic Press, Inc. Received May 26, 1978. Supported by the Public Health Service, Research Grant No. GM-11072 from the Division of General Medical Sciences, and by the National Science Foundation.Additional details
- Eprint ID
- 61481
- DOI
- 10.1016/0006-291X(78)91037-9
- Resolver ID
- CaltechAUTHORS:20151023-101624893
- U.S. Public Health Service (USPHS)
- GM-11072
- NSF
- Created
-
2015-10-26Created from EPrint's datestamp field
- Updated
-
2021-11-10Created from EPrint's last_modified field
- Other Numbering System Name
- Caltech Gates and Crellin Laboratories of Chemistry
- Other Numbering System Identifier
- 5793