Published February 1981
| public
Journal Article
Examination of the Aspirin Acetylation Site of Human Serum Albumin by ^(13)C NMR spectroscopy
Chicago
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Abstract
Human serum albumin has been specifically acetylated using aspirin in which the methyl carbon of the acetyl group was enriched to 90% ^(13)C. A single resonance at 23.13 ppm downfield from tetramethylsilane was observed in ^(13)C differences spectra obtained at both 25.2 and 45.3 MHz. Chemical shift studies of several model compounds suggest that this is the resonance position to be expected for an acetamide group exposed to solvent. The line width observed for the enriched methyl resonance is consistent with free rotation of the methyl group.
Additional Information
© 1981 Heyden & Son Ltd. Received 15 April 1980; accepted 22 July 1980. Work at the University of California was supported by Grants CA-11220 and GM-25975 from the National Institutes of Health. Work at the California Institute of Technology was supported by Grant GM-11072.Additional details
- Eprint ID
- 60797
- Resolver ID
- CaltechAUTHORS:20151006-073240976
- NIH
- CA-11220
- NIH
- GM-25975
- U.S. Public Health Service (USPHS)
- GM-11072
- Created
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2015-10-06Created from EPrint's datestamp field
- Updated
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2021-11-10Created from EPrint's last_modified field