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Published 1983 | Published
Journal Article Open

Gene Expression and the Diversity of Identified Neurons

Abstract

Nervous systems consist of diverse populations of neurons that are anatomically and functionally distinct. The diversity of neurons and the precision with which they are interconnected suggest that specific genes or sets of genes are activated in some neurons but not expressed in others. Experimentally, this problem may be considered at two levels. First, what is the total number of genes expressed in the brain, and how are they distributed among the different populations of neurons? Second, can we identify specific genes expressed in individual neurons and relate the expression of these genes to the unique functional properties of these neurons?

Additional Information

© 1983 Cold Spring Harbor Laboratory Press. The Authors acknowledge that six months after the full-issue publication date, the Article will be distributed under a Creative Commons CC-BY-NC License (Attribution-NonCommercial 4.0 International License, http://creativecommons.org/licenses/by-nc/4.0/). This work was supported by a grant from the National Institutes of Health to R.A. and by fellowships from the Cancer Research Institute, Inc., to L.B., from the National Institutes of Health to R.S., and from the Helen Hay Whitney Foundation to D.A.

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Created:
August 19, 2023
Modified:
October 23, 2023