Published December 2004
| public
Journal Article
The genetics of cell death: approaches, insights and opportunities in Drosophila
- Creators
- Hay, Bruce A.
- Huh, Jun R.
- Guo, Ming
Chicago
An error occurred while generating the citation.
Abstract
Cell death is ubiquitous in metazoans and involves the action of an evolutionarily conserved process known as programmed cell death or apoptosis. In Drosophila melanogaster, it is now uniquely possible to screen for genes that determine the fate — life or death — of any cell or population of cells during development and in the adult. This review describes these genetic approaches and the key insights into cell-death mechanisms that have been obtained, as well as the outstanding questions that these techniques can help to answer.
Additional Information
© 2004 Nature Publishing Group. Work in the authors' laboratories is supported by NIH (National Institutes of Health) grants. We apologize to authors whose work could not be cited directly owing to space limitations.Additional details
- Eprint ID
- 56497
- DOI
- 10.1038/nrg1491
- Resolver ID
- CaltechAUTHORS:20150408-150756595
- NIH
- Created
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2015-04-08Created from EPrint's datestamp field
- Updated
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2021-11-10Created from EPrint's last_modified field