Published March 2007 | public
Journal Article

The neuropoietic cytokine family in development, plasticity, disease and injury

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Abstract

Neuropoietic cytokines are well known for their role in the control of neuronal, glial and immune responses to injury or disease. Since this discovery, it has emerged that several of these proteins are also involved in nervous system development, in particular in the regulation of neurogenesis and stem cell fate. Recent data indicate that these proteins have yet more functions, as key modulators of synaptic plasticity and of various behaviours. In addition, neuropoietic cytokines might be a factor in the aetiology of psychiatric disorders.

Additional Information

© 2007 Nature Publishing Group. We thank K. Hamilton for help in preparing the manuscript, and D. McDowell and B. Lease for administrative support on the work done in the Patterson laboratory. Our research discussed here was supported by grants from the National Institute of Neurological Disease and Stroke, the John Douglas French Alzheimer's Foundation, the McGrath Foundation, a Cline Neuroscience Discovery Grant, and the Roman Reed Spinal Cord Injury Research Fund of California.

Additional details

Created:
August 19, 2023
Modified:
October 20, 2023