Published July 1997
| public
Journal Article
Cellular and molecular biology of neural crest cell lineage determination
- Creators
-
Anderson, David J.
Chicago
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Abstract
The past few years have seen an explosion of information about genes that control the development of the neural crest, a structure unique to vertebrate embryogenesis. Many of these genes are mutated in human diseases that affect crest-derived lineages. At the same time, decades of work on the neural crest at the cellular level are generating new insights into the segregation of different lineages and the role played by environmental signals in the lineage-commitment process. The challenge now is to integrate the cellular and molecular genetic perspectives on neural crest development. This review attempts such a synthesis.
Additional Information
© 1997 Elsevier Science. Available online 10 December 1997. Work described from the author's laboratory was supported by the NIH, Muscular Dystrophy Association and the Howard Hughes Medical Institute. I thank members of my laboratory for helpful discussions, and Nirao Shah for the preparation of Fig.1Additional details
- Eprint ID
- 55257
- DOI
- 10.1016/S0168-9525(97)01187-6
- Resolver ID
- CaltechAUTHORS:20150226-111906850
- NIH
- Muscular Dystrophy Association
- Howard Hughes Medical Institute (HHMI)
- Created
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2015-02-26Created from EPrint's datestamp field
- Updated
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2021-11-10Created from EPrint's last_modified field