Published November 4, 1983
| public
Journal Article
A Micromechanical Contribution to Cochlear Tuning and Tonotopic Organization
- Creators
- Holton, Thomas
- Hudspeth, A. J.
Abstract
The response properties of hair cells and nerve fibers in the alligator lizard cochlea are frequency selective and tonotopically organized with longitudinal position in the organ. The lengths of the hair-cell hair bundles also vary monotonically with longitudinal position. In this study, quantitative measurements were made of the motion of individual hair bundles in an excised preparation of the cochlea stimulated at auditory frequencies. The angular displacement of hair bundles is frequency selective and tonotopically organized, demonstrating the existence of a micromechanical tuning mechanism.
Additional Information
© 1983 American Association for the Advancement of Science. 28 February 1983; accepted 25 July 1983. Supported by fellowships to T.H. from the Del E. Webb Foundation and the National Institutes of Health (GM07301) and grants to A.J.H. from NIH (NSl3l54) and the System Development Foundation. We thank J. N. Power for electronic design and construction, R. Jacobs for technical assistance, and H. Berg, R. A. Eatock, M. Konishi, R. S. Lewis, and D. C. Van Essen for comments on the manuscript.Additional details
- Eprint ID
- 54414
- DOI
- 10.1126/science.6623089
- Resolver ID
- CaltechAUTHORS:20150205-095841191
- Del E. Webb Foundation
- GM07301
- NIH
- NS13154
- NIH
- System Development Foundation
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2015-02-05Created from EPrint's datestamp field
- Updated
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2021-11-10Created from EPrint's last_modified field