Published February 5, 1982
| public
Journal Article
DNA Sequence of a Gene Encoding a BALB/c Mouse L^d Transplantation Antigen
Abstract
The sequence of a gene, denoted 27.5, encoding a transplantation antigen for the BALB/c mouse has been determined. Gene transfer studies and comparison of the translated sequence with the partial amino acid sequence of the L^d transplantation antigen establish that gene 27.5 encodes an L^d polypeptide. A comparison of the gene 27.5 sequence with several complementary DNA sequences suggests that the BALB/c mouse may contain a number of closely related L-like genes. Gene 27.5 has eight exons that correlate with the structural domains of the transplantation antigen.
Additional Information
© 1982 American Association for the Advancement of Science. 5 November 1981 ; revised 16 December 1981. Supported by NIH grant GM 06965. K.W.M. was initially supported by a postdoctoral fellowship from the National Institutes of Health. B.T.S. was supported by a predoctoral fellowship from the National Science Foundation. Y.H.S. and K.A.E.were supported by a national research service award (I T32 GM07616) from the National Institute of General Medical Sciences. We thank M. Douglas for computer graphics, T. Hunkapiller for computer programs, and B. Larsh for manuscript preparation. We thank W. R. Jelinek for pointing out the presence of several Alu-like sequences in gene 27.1.Additional details
- Eprint ID
- 54391
- Resolver ID
- CaltechAUTHORS:20150204-153430736
- GM 06965
- NIH
- NIH Fellowship
- NSF Predoctoral Fellowship
- I T32 GM07616
- National Institute of General Medical Sciences
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