Published August 5, 1983
| public
Journal Article
Expression of the Major Neurofilament Subunit in Chicken Erythrocytes
- Creators
- Granger, Bruce L.
- Lazarides, Elias
Abstract
The 70,000-dalton core polypeptide of neurofilaments, thought to exist only in neurons, has been detected in chicken erythrocytes, where it coexists with vimentin and synemin as a component of the intermediate filament network. It is present in the circulating erythroid cells of embryos and young chickens but is nearly absent from the erythroid cells of adults. These findings are inconsistent with current models of intermediate filament expression, but provide another example of unexpected similarities between the nervous and hemopoietic systems.
Additional Information
© 1983 American Association for the Advancement of Science. Received 4 March 1983. Supported by grants from the NIH [T32 GM07616 (B .G.), RCDA (E.L.), BRSG RR07003, and GM06965), NSF, and MDA. B.G. was also supported by a postdoctoral fellowship from the MDA. We thank W. J. Nelson, J. Ngai, R. D. Owen, and J.-P. Revel for critical reading of the manuscript.Additional details
- Eprint ID
- 53838
- DOI
- 10.1126/science.6346488
- Resolver ID
- CaltechAUTHORS:20150116-141548264
- T32 GM076165
- NIH
- RR07003
- NIH
- GM06965
- NIH
- NSF
- Muscular Dystrophy Association
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2015-01-17Created from EPrint's datestamp field
- Updated
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2021-11-10Created from EPrint's last_modified field