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Published July 26, 2007 | public
Journal Article

Synthesis of the functionalizable methionine surrogate azidohomoalanine using Boc-homoserine as precursor

Abstract

This protocol describes a synthetic route to the non-canonical amino acid azidohomoalanine (AHA) using protected homoserine as a starting material. An alternative route to AHA is presented in a companion paper. This synthesis can be completed in 5 days.

Additional Information

This work was supported by NIH, by an NSF graduate fellowship to A.J.L. and by a grant from the Netherlands Organization for Scientific Research to M.K.S.V.

Additional details

Created:
August 19, 2023
Modified:
October 19, 2023